Faculty
David Ballou Collegiate Professor of Biological Chemistry
Research:
Enzyme mechanisms, metals in biology, redox regulation
Professor of Medicinal Chemistry; Professor of Pharmacology; Professor of Biophysics
Research:
Understanding how the functions of human cytochrome P450 enzymes in drug metabolism and in normal physiology (e.g. steroidogenesis) are controlled by the molecular details of specific P450/ligand interactions. Using X-ray crystallography, NMR, and other structural and biophysical techniques, the goal is to facilitate the design of drugs to improve human health across many different human diseases including cancers.
Assistant Professor of Internal Medicine; Assistant Professor of Medicinal Chemistry; Faculty Lead, Drug Repurposing, MICHR
Research:
Drug discovery, drug repurposing and drug development for diabetes and obesity
Research Professor, Life Sciences Institute; Hans W. Vahlteich Professor of Medicinal Chemistry; Professor of Chemistry; Professor of Microbiology and Immunology
Research:
Synthetic chemistry, marine microorganisms, drug discovery
- Director of the Center for Structural Biology, Life Sciences Institute
Margaret J Hunter Collegiate Professor, Life Sciences Institute; Professor of Biological Chemistry
Research:
Protein structure and function using X-ray crystallography
Professor of Pharmacology; Professor of Biophysics; Benedict R Lucchesi Collegiate Professor of Cardiovascular Pharmacology
Research:
The interactions between the G proteins and their protein targets at a molecular and structural level with the goal of understanding how these interactions lead to alterations in protein and cellular activities
Assistant Professor of Chemistry; Research Associate Professor of Internal Medicine (Adjunct)
Research:
Chemical and cell biology of protein kinases
Associate Professor of Molecular, Cellular, and Developmental Biology
Research:
Structure/function of membrane proteins, microbial fluoride resistance
- Director of the Pharmacokinetics Core, College of Pharmacy
J G Searle Endowed Professor of Pharmaceutical Sciences
Research:
Drug discovery for cancer therapy; Nanotechnology for drug delivery and vaccine delivery; Pharmacokinetics and drug optimization
Professor of Pharmacology
Research:
G protein signaling and new classes of enzymes that activate heterotrimeric G proteins apart from GPCR-initiated activation
- Albert M. Mattocks Professor of Pharmaceutical Sciences and Chemical Engineering
Research:
Therapeutic protein design, directed evolution, engineering, formulation and delivery
Professor of Biological Chemistry, Medical School
Research:
Chemical and structural biology of protein posttranslational modifications
Assistant Professor of Molecular and Integrative Physiology; Research Assistant Professor, Institute of Gerontology
Research:
Post-translational protein modification in neuro-degeneration and aging
Professor of Biophysics; Professor of Physics
Research:
Physical properties of plasma membrane lipids
Associate Professor of Molecular, Cellular, and Developmental Biology; Associate Professor of Biophysics
Research:
Mechanisms of Subcellular Organization in Bacteria