Faculty
Professor of Chemistry; Professor of Biological Chemistry
Research:
Enzyme mechanism and structure, protein design
Arthur F. Thurnau, Margaret and Herman Sokol Professor in Medicinal or Synthetic Chemistry; Arthur F. Thurnau Professor of Chemistry
Research:
Synthetic Chemistry and Glycoscience
Assistant Professor of Human Genetics; Faculty Scholar, Center for RNA Biomedicine
Research:
Mechanisms of RNA regulation in stress, aging, and neurological disease
Research Assistant Professor, Life Sciences Institute; Assistant Professor of Cellular & Developmental Biology; Assistant Professor of Biological Chemistry
Research:
In-situ structural biology
Professor of Chemistry
Research:
Natural products with anticancer activity, synthesis, medicinal chemistry, cardiotonic steroids
- Associate Director of Graduate Students, Program in Chemical Biology
Professor of Molecular, Cellular, and Developmental Biology
Research:
Telomerase, telomeres, cancer, aging biochemistry
Assistant Professor of Biological Chemistry; Faculty Scholar, Center for RNA Biomedicine
Research:
mRNA regulatory features that control protein output
- Director of Molecular and Cellular Pathology Graduate Program, Medical School
Professor of Pathology
Research:
Discovery, design and development of small molecules as new molecularly targeted therapies for cancer
- Associate Chair of Biological Chemistry
Professor of Biological Chemistry
Research:
Protein/nucleic acid interactions and DNA repair
- Rowena G. Matthews Collegiate Professor in the Life Sciences
Professor of Cell and Developmental Biology
Research:
Using single particle cryo-electron microscopy (cryo-EM) in combination with biophysical, biochemical, and genetic approaches to structurally and functionally characterize biologically important but structurally challenging molecular machines.
Professor of Cell and Developmental Biology
Research:
Mitosis, Cytokinesis, Microtubule, Kinesin, Microscopy, Reconstitution
Warner-Lambert/Parke-Davis Professor in Medicine; Professor of Pharmacology; Associate Chair, Innovation and Wellness
Research:
Protein folding diseases; Hsp90, Hsp70; molecular chaperones; nitric oxide synthase; ubiquitination and protein quality control; reactive metabolites and mass spectrometry.
Associate Professor of Biological Chemistry
Research:
We investigate the reaction mechanisms of flavin-dependent enzymes, especially the reactions of O2 and the formation of novel intermediates, using kinetic, spectroscopy, and anything else that helps. Flavoenzymes are constantly being discovered in all areas of biology, making them inviting drug targets, models for detailed studies of structure-function relationships and enzyme evolution. And surprisingly, despite decades of intense enzymology, novel intermediates continue to be discovered
- Raymond and Lynne Ruddon Professor of Cancer Biology and Pharmacology
- Professor of Cell and Developmental Biology; Research Professor, U-M Life Sciences Institute
Pharmacology, School of Medicine; Cell & Developmental Biology, School of Medicine
Research:
Immune cell migration in the context of inflammation and cancer.
John T Groves Collegiate Professor of Chemistry
Research:
The role of metals in biology. Metalloprotein Design of redox and hydrolytic enzymes and electron transfer proteins. Development of Near Infrared luminescent imaging agents for cellular and animal studies.